Compositions and methods for prevention of escape mutation in the treatment of Her2/neu over-expressing tumors

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专利权人:

Inc.;Advaxis

发明人:

Shahabi, Vafa

申请号：

AU2012296474

公开号：

AU2012296474B2

申请日:

2012.08.16

申请国别(地区):

AU

年份:

2017

代理人:

摘要：

This invention provides compositions and methods for treating and vaccinating and inducing an immune response against a Her2/neu antigen-expressing tumor in a non-human animal. An exemplary method of treating a Her-2/neu-expressing tumor growth or cancer in a non-human animal, the method comprising the step of administering a recombinant Listeria comprising nucleic acid molecule encoding a fusion polypeptide, wherein said fusion polypeptide comprises a Her2/neu chimeric antigen fused to an additional adjuvant polypeptide is provided.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/