Formula (I), wherein A is unsubstituted or substituted phenyl； or a ~ membered aromatic containing 1 or 2 heteroatoms independently selected from the group consisting of N and O Represents a 9- or 10-membered bicyclic group consisting of a benzene ring fused to a heterocycle and connected to-(C) x- (CH2) y- through one of its aromatic carbon atoms Wherein such bicyclic groups are unsubstituted or substituted with a 5 or 6 membered non-aromatic heterocyclic ring having one or two O atoms, wherein the heterocyclic group The ring of is unsubstituted or substituted with one or more C1-C3-alkyl； D is unsubstituted or substituted phenyl； unsubstituted or substituted Naphthyl； unsubstituted or substituted thiophene； 5-membered A bicyclic group consisting of an imidazole ring fused to a Group carbocyclic ring； N, unsubstituted or substituted and connected to the sulfonamide moiety through one of the carbon atoms of the benzene ring, A bicyclic group comprising a benzene ring having one or two heteroatoms independently selected from the group consisting of O and S and fused with a 5-membered aromatic heterocycle； and unsubstituted Or a member or 6 having 1 or 2 heteroatoms independently selected from the group consisting of N and O, substituted and connected to the sulfonamide moiety through one of the carbon atoms of the benzene ring Represents a group selected from a bicyclic group consisting of a benzene ring fused with a member non-aromatic heterocyclic group； R represents H or —CH 3； x is 0 or 1； y Is represented by 2 or 3 Sulfonamide derivatives of benzylamine and pharmaceutically acceptable salts and solvates thereof, provided that x is 0 and y is 2, then D is unsubstituted or substituted with one halogen atom Naphthyl； and if R represents —CH 3, then A is not unsubstituted or substituted phenyl. The compounds can be used in the treatment and / or prevention of central nervous system disorders.式（Ｉ）、式中Ａは、非置換であるかまたは置換されたフェニル；あるいはＮおよびＯからなる群から独立して選択される１つまたは２つのヘテロ原子を含有する～員
