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Sulphonamide derivatives of alicyclic amines for the treatment of central nervous system diseases
专利权人:
Adamed Sp. z o.o.
发明人:
Kolaczkowski, Marcin,Marcinkowska, Monika,Bucki, Adam,Pawlowski, Maciej,Krukowski, Andrzej,Rusiecki, Rafal,Siwek, Agata Magdalena,Wolak, Malgorzata Anna
申请号:
AU2012277364
公开号:
AU2012277364A1
申请日:
2012.06.29
申请国别(地区):
AU
年份:
2014
代理人:
摘要:
Sulphonamide derivatives of alicyclic amines of formula (I), wherein A represents naphthyl or 9- or 10-membered bicyclic group, consisting of benzene ring fused with -or 6-membered heterocyclic ring; D represents phenyl, naphthyl, 5-membered aromatic heterocyclic group, bicyclic group consisting of a ring selected from benzene and pyridine, fused with aromatic or non-aromatic 5-membered heterocyclic ring; r represents 0 or 1; x, z independently represent 1 or 2; n represents 3 and p represents 0, or n represents 2 and p represents 1;and enantiomers, pharmaceutically acceptable salts and solvates thereof. The compounds may be useful for the treatment and/or prevention of the central nervous system disorders (Formula I).
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