SRINIVASAN, Shanmugam,IM, Ho Taek,YOON, Young Su,KIM, Yong Il,PARK, Jae Hyun,WOO, Jong Soo
申请号:
EP15773354
公开号:
EP3125872A4
申请日:
2015.03.20
申请国别(地区):
EP
年份:
2017
代理人:
摘要:
Provided is an amorphous solid dispersion including a taxane or a pharmaceutically acceptable salt thereof, a pharmaceutically acceptable polymer, and a pharmaceutically acceptable surfactant, which has enhanced solubility. Also provided is a method for preparing the solid dispersion. The present subject matter also provides a tablet having good solubility, bioavailability and stability, which comprises the amorphous solid dispersion, an intragranular excipient, and an extragranular excipient.