Srinivasan, Shanmugam,Im, Ho Taek,Yoon, Young Su,Kim, Yong Il,Park, Jae Hyun,Woo, Jong Soo
申请号：
AU2015242738
公开号：
AU2015242738B2
申请日:
2015.03.20
申请国别(地区):
AU
年份:
2019
代理人:
摘要：
The present invention provides an amorphous solid dispersion comprising a taxane or a pharmaceutically acceptable salt thereof, a pharmaceutically acceptable polymer, and a pharmaceutically acceptable surfactant, which has enhanced solubility. Also provided is a method for preparing the solid dispersion. The present invention also provides a tablet having good solubility, bioavailability and stability, which comprises the amorphous solid dispersion, an intragranular excipient, and an extragranular excipient.
