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AMORPHOUS SOLID DISPERSION COMPRISING TAXANE, TABLET COMPRISING THE SAME, AND METHOD FOR PREPARING THE SAME
专利权人:
HANMI PHARM. CO.; LTD.
发明人:
SRINIVASAN, SHANMUGAM,IM, HO TAEK,YOON, YOUNG SU,KIM, YONG IL,PARK, JAE HYUN,WOO, JONG SOO
申请号:
PH12016501825
公开号:
PH12016501825A1
申请日:
2016.09.19
申请国别(地区):
PH
年份:
2016
代理人:
摘要:
The present invention provides an amorphous solid dispersion comprising a taxane or a pharmaceutically acceptable salt thereof, a pharmaceutically acceptable polymer, and a pharmaceutically acceptable surfactant, which has enhanced solubility. Also provided is a method for preparing the solid dispersion. The present invention also provides a tablet having good solubility, bioavailability and stability, which comprises the amorphous solid dispersion, an intragranular excipient, and an extragranular excipient.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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