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ISFET ARRAY FOR DETECTING A SINGLE NUCLEOTIDE POLYMORPHISM
专利权人:
发明人:
申请号:
KR20147028959
公开号:
KR20150013128(A)
申请日:
2013.03.19
申请国别(地区):
韩国
年份:
2015
代理人:
摘要:

Apparatus comprising a module for detecting a single nucleotide polymorphism, SNP, within a genome and comprising: four reaction chambers for receiving a fluid sample, the reaction chambers each containing a different one of the bases A, C, G, T, and a primer; a reference electrode which in use is immersed in said fluid sample; a pair of Ion Sensitive Field Effect Transistors, ISFETs, associated with each reaction chamber, the ISFETs of each pair comprising respective sensing membranes, or a common sensing membrane, exposed within the associated reaction chamber; and a plurality of difference detectors, each difference detector having a pair of inputs coupled respectively to outputs of ISFETs associated with different reaction chambers.

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