EGRIE, Joan C.,ELLIOTT, Steven G.,BROWN, Jeffrey K.
申请号：
ES99955046
公开号：
ES2283139T5
申请日:
1999.10.18
申请国别(地区):
ES
年份:
2018
代理人:
摘要：
Methods for increasing and maintaining hematocrit in a mammal comprising administering a hyperglycosylated analog of erythropoietin are disclosed. An analog may be administered less frequently than an equivalent molar amount of recombinant human erythropoietin to obtain a comparable target hematocrit and treat anemia. Alternatively, a lower molar amount of a hyperglycosylated analog may be administered to obtain a comparable target hematocrit and treat anemia. Also disclosed are new hyperglycosylated erythopoietin analogs, methods of production of the analogs, and compositions comprising the analogs.
