Joan C. EGRIE,Steven G. Elliot,Jeffrey K. Browne,Karen C. Sitney
申请号：
US13589026
公开号：
US20120322730A1
申请日:
2012.08.17
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Methods for increasing and maintaining hematocrit in a mammal comprising administering a hyperglycosylated analog of erythropoietin are disclosed. An analog may be administered less frequently than an equivalent molar amount of recombinant human erythropoietin to obtain a comparable target hematocrit and treat anemia. Alternatively, a lower molar amount of a hyperglycosylated analog may be administered to obtain a comparable target hematocrit and treat anemia. Also disclosed are new hyperglycosylated erythopoietin analogs, methods of production of the analogs, and compositions comprising the analogs.
