EGRIE, JOAN C.,ELLIOTT, STEVEN G.,BROWN, JEFFREY K.
申请号:
HU0103920
公开号:
HU228492B1
申请日:
1999.10.18
申请国别(地区):
HU
年份:
2013
代理人:
摘要:
Methods for increasing and maintaining hematocrit in a mammal comprising administering a hyperglycosylated analog of erythropoietin are disclosed. An analog may be administered less frequently than an equivalent molar amount of recombinant human erythropoietin to obtain a comparable target hematocrit and treat anemia. Alternatively, a lower molar amount of a hyperglycosylated analog may be administered to obtain a comparable target hematocrit and treat anemia. Also disclosed are new hyperglycosylated erythopoietin analogs, methods of production of the analogs, and compositions comprising the analogs.