COMPOSES DE CARFILZOMIB PEGYLES

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专利权人:

AMGEN INC.

发明人:

LUEHR, GARY,ANIK, SHABBIR T.,PENG, GE,DOTSENKO, IRINA,PHIASIVONGSA, PASIT,ROMANINI, DANTE

申请号：

CA3025170

公开号：

CA3025170A1

申请日:

2017.05.23

申请国别(地区):

CA

年份:

2017

代理人:

摘要：

The present invention provides polymeric pegylated carfilzomib compounds, and pharmaceutically acceptable salts thereof, of Formula I wherein R1, R2, linker, PEG, n and o are as defined herein. The invention also provides methods of making and using these compounds to treat cancer, and particularly to treat hematological malignancies including multiple myeloma.

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中国工程科技知识中心

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