PEGYLATED CARFILZOMIB COMPOUNDS

• 收藏
• 分享

专利权人:

AMGEN INC.

发明人:

ANIK, Shabbir T.,DOTSENKO, Irina,LUEHR, Gary,PENG, Ge,PHIASIVONGSA, Pasit,ROMANINI, Dante

申请号：

TN2018000393

公开号：

TN2018000393A1

申请日:

2017.05.23

申请国别(地区):

TN

年份:

2020

代理人:

摘要：

The present invention provides polymeric pegylated carfilzomib compounds, and pharmaceutically acceptable salts thereof, of Formula 1 wherein R<；sup>；1<；/sup>；, R<；sup>；2<；/sup>； , linker, PEG, n and o are as defined herein. The invention also provides methods of making and using these compounds to treat cancer, and particularly to treat hematological malignancies including multiple myeloma.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/