Gary Luehr,Shabbir T. Anik,Ge Peng,Irina Dotsenko,Pasit Phiasivongsa,Dante Romanini
申请号：
US15602823
公开号：
US10517954B2
申请日:
2017.05.23
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The present invention provides polymeric pegylated carfilzomib compounds, and pharmaceutically acceptable salts thereof, of Formula Iwherein R1, R2, linker, PEG, n and o are as defined herein. The invention also provides methods of making and using these compounds to treat cancer, and particularly to treat hematological malignancies including multiple myeloma.
