Fritz Aberger,Wolfgang Gruber,Johann Leban,Hella Kohlhof,Daniel Vitt,Roland Baumgartner
申请号:
US14307533
公开号:
US09951050B2
申请日:
2014.06.18
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention relates to a DYRK1B inhibitor for use in the treatment of cancer, wherein in said cancer and/or in cells of said cancer the hedgehog signaling pathway is activated, and in particular the activation of the hedgehog signaling pathway is independent of signaling by the G protein-coupled receptor Smoothened.