Fritz ABERGER,Wolfgang GRUBER,Johann LEBAN,Hella KOHLHOF,Daniel VITT,Roland BAUMGARTNER
申请号:
US15915626
公开号:
US20180201606A1
申请日:
2018.03.08
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention relates to a DYRK1B inhibitor for use in the treatment of cancer, wherein in said cancer and/or in cells of said cancer the hedgehog signaling pathway is activated, and in particular the activation of the hedgehog signaling pathway is independent of signaling by the G protein-coupled receptor Smoothened.