Daniel Holsworth,Jo Waaler,Ondrej Machon,Stefan Krauss
申请号:
US13376202
公开号:
US20120208828A1
申请日:
2010.06.07
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention relates to new compounds of formula I, to processes for their preparation, to pharmaceutical formulations containing such compounds and to their use in therapy. Such compounds find particular use in the treatment and/or prevention of conditions or diseases which are affected by over-activation of signaling in the Wnt pathway. For example, these may be used in preventing and/or retarding proliferation of tumor cells, for example carcinomas such as colon carcinomas.