THE UNIVERSITY OF BRITISH COLUMBIA;PROMIS NEUROSCIENCES INC.
发明人:
Neil R. Cashman,Steven S. Plotkin,Johanne Kaplan,Judith Maxwell Silverman,Ebrima Gibbs
申请号：
US16631676
公开号：
US20200181247A1
申请日:
2018.07.18
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The disclosure pertains to antibodies that bind A-beta oligomers and methods of making and using said antibodies. Also provided are chimeric or humanized antibodies, including antibodies having CDRs in Table 2 and/or having a sequence as set forth in Table 4B or a sequence with at least 50% sequence identity thereto optionally wherein the CDR amino acid sequences are as set for forth in SEQ ID Nos: 74-79. Also provided are methods and uses thereof as well as kits comprising said antibodies.
