Research of Institute Nationwide Children's Hospital;Research of Institute Nationwide Childrens Hospital;Ohio State Innovation Foundation
发明人:
Li, Chenglong,Yu, Wenying,Lin, Jiayuh
申请号：
AU2013302390
公开号：
AU2013302390A1
申请日:
2013.08.16
申请国别(地区):
AU
年份:
2015
代理人:
摘要：
In one aspect, the invention relates to substituted substituted 6-amino-5,8-dioxo-5,8- dihydronaphthalene- 1 -sulfonamide analogs and derivatives thereof, substituted 4-amino-5H- naphtho[l,8-cd]isothiazol-5-one 1,1-dioxide analogs and derivatives thereof, and related compounds, which are useful as inhibitors of STAT protein activity； synthetic methods for making the compounds； pharmaceutical compositions comprising the compounds； and methods of treating disorders of uncontrolled cellular proliferation associated with a STAT protein activity dysfunction using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
