Kárpáti, Richard Balázs,Patyi, Gergö,Basa-Dénes, Orsolya,Angi, Erzsébet Réka,Jordán, Tamás,Solymosi, Tamás,Glavinas, Hristos,Filipcsei, Genovéva
申请号：
AU2017256180
公开号：
AU2017256180A1
申请日:
2017.04.25
申请国别(地区):
AU
年份:
2018
代理人:
摘要：
The present invention relates to pharmaceutically acceptable complex formulations comprising complexes of Ivacaftor, or a salt, or derivatives thereof and complexation agents and pharmaceutically acceptable excipients, process for the preparation thereof and pharmaceutical compositions containing them. The complexes of the present invention possess instantaneous redispersibility, increased apparent solubility and permeability, no observable food effect which deliver the opportunity of precise dosing and ease of administration of the reconstituted complex Ivacaftor in solution form.
