Claim 1: a Compound, characterized in that it is the General Chemical formula (1), wherein R1, R2, R3 and R4 are independently of each other, hydrogen or Fluorine, where at least one Substituent selected from R1, R2, R3 and R4 is Fluorine； R5, R6 and R7 are independent manner And among them, Hydrogen, Fluorine, Chlorine, Bromine, Methyl, Ethyl,Trifluoromethyl or Nitrile； X is selected from the group consisting of hydrogen, alkyl - C1 - 6 - - 8 - - - cicloalquil C3, C2 alquenilo - 6, 6 - alquinilo C2, C1 - alkyl - 6 - S (o) - 2, 6 - alquilcarbonil C1 alkyl, phenyl - C1 - 6 Optionally, It can be mono -, di - or polisustituido with Halogen, - Oh, - CN, - nr8r9, Nr10r11, - C (o) - N (R10) C (o) - nr10r11 haloalcoxi C1, C1 - 6 - alkoxy -, 6 -, - C (o) o- C (o) or alkyl C1 - 6 or - C (o) - benzyl or optionally you can also change Atoms of hydrogen by deuterium ATOMS, R8 and R9 are alkyl, cycloalkyl C3 C1 - 6, - 7, optionally substituted phenyl or benzyl Halogen deuterium or Hydrogen； R10 and R11 are alkyl or cycloalkyl C1 - C3 - 7 6PHENYL or benzyl or optionally substituted with deuterium and Halogen； is a c1-4 alkyl or cycloalkyl perfluorinated and partially fluorinated C3 - 8 perfluorinated and partially fluorinated； M is 4, 5, 6 or 7； n is 2, 3, 4, 5 or 6, p is 0, 1 or 2； Q is 0, 1, 2, 3, 4, 5 or 6； and a Salt, Salt or solvate Crystalline solvate, including all modifications, the same, the same.Use of a compound claim 10: defined in any of claims 1 to 5, wherein it is to prepare a drug to induce ovulation, to inhibit the maturation of sperm； to alleviate the symptoms of Menopause and Andropause, i.e. for Therapy Male and Female hormone replacement.For Prevention and for the Treatment or prophylaxis of discomfort that accompany dysmenorrhoea, dysfunctional uterine Bleeding, acne, cardiovascular disease, Hypercholesterolemia, atherosclerosis, the Proliferation of arterial smooth muscle cells, d Respiratory Distress Syndrome in the newbornThe Blood of primary pulmonary hy
