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ЗАМЕЩЕННЫЕ 4-(АРИЛАМИНО) СЕЛЕНОФЕНОПИРИМИДИНОВЫЕ СОЕДИНЕНИЯ И СПОСОБЫ ИХ ПРИМЕНЕНИЯ
专利权人:
KASINA LAJLA INNOVA FARMASJUTIKALZ PRAJVIT LIMITED;KASINA LAJLA INNOVA FARMAS'JUTIKALZ PRAJVIT LIMITED
发明人:
GOKARADZHU GANGA RADZHU,KASINA SUDKHAKAR,SOMEPALLI VENKATESVARLU,GOKARADZHU RAMA RADZHU,GOKARADZHU VENKATA KANAKA RANGA RADZHU,BKHUPATKHIRADZHU KIRAN,GOLAKOTI TRIMURTULU,SENGUPTA KRISHANU,ALLURI VENKA,ГОКАРАДЖУ Ганга Раджу,КАСИНА Судхакар,СОМЕПАЛЛИ Венкатесварлу,ГОКАРАДЖУ Рама Раджу,GOKARADZHU VENKATA KANAKA RAN
申请号:
RU2013131268
公开号:
RU2566293C2
申请日:
2011.12.07
申请国别(地区):
RU
年份:
2015
代理人:
摘要:
FIELD: medicine, pharmaceutics.SUBSTANCE: invention relates to selenophene compound of formula (I)or its pharmaceutically acceptable salt. X stands for selenium, Y and Z stand for carbon atoms; or Y stands for selenium, X and Z stand for carbon atoms; or Z stands for selenium, X and Y stand for carbon atoms; A stands for N; B stands for NR, where Ris selected from hydrogen, or alkyl; Ar stands for aryl or heteroaryl ring; aryl represents benzene or naphthalene ring, and heteroaryl represents 6-membered aromatic ring, which contains one, two or three nitrogen atoms; or heteroaryl stands for 5-membered aromatic ring, which contains one or several heteroatoms, selected from sulphur, oxygen and nitrogen, on condition that not more than one oxygen or sulphur atom is present; and such rings include pyridine, pyridazine, pyrazine, pyrimidine, thiophene, furan, pyrrole, pyrazole, imidazole, oxazole, isoxazole, thiazole and isothiazole; optionally substituted with one, two or several groups, independently selected from hydrogen, halogen, thiol, sulphonamide, Calkyl, secondary Calkyl, tertiary Calkyl, Calkinyl, Calkoxycarbonyl and phenyl; R, Rand Rare independently selected from hydrogen, carboxylic acid, amino, nitro, cyano, sulphonic acid, thiol, trihalomethyl, Calkyl, secondary Calkyl, tertiary Calkyl, Calkoxycarbonyl, aminocarbonyl, Calkylaminocarbonyl, di(Calkyl)aminocarbonyl, and phenyl; or Rand Rare bound, and together with atoms, which they are bound to, they form 5-7-membered optionally substituted carbocyclic or perhydroheterocyclic ring, given in invention formula; or Rand Rare bound, and together with atoms, which they are bound to, form optionally substituted aryl or non-substituted heteroaryl ring, fused with selenophene; and aryl represents benzene ring, and heteroaryl represents 6-membered aromatic ring, which contains one nitrogen atom. Methods of obtaining selenophene compound (versions), pharmaceutical composition, methods of treatment or inhibition, or con
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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