The invention relates to a method for the production of a biologically active prosthetic device for the reconstruction of bone tissue comprising the steps of a CAT (Computerized Axial Tomography) scan of the patient and obtaining a three-dimensional electronic mode] (1) of the part of the bone and of a bone defect (2) to be reconstructed, production by prototyping of a prototype resin mode] (3) of the area of the patient s bone involved, forming of a model (4), of the patient s bone defect to be reconstructed, construction of a netative mould (5), production of a ready sintered ceramic semi-finished product with controlled and interconnected porosity, said semi-finished product being made with dimensions and shape slightly larger than the bone defect mechanical processing and manna] finishing of the sintered semi-finished product, to obtain the precise dimensions and shape of the bone defect, the invention also relating to the prosthetic device obtained using the method described above.