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PROCESSO PARA PRODUÇÃO DE CLORIDRATO DE PRASULGREL COM PUREZA ELEVADA
专利权人:
UBE INDUSTRIES LIMITED;DAIICHI SANKYO COMPANY, LIMITED
发明人:
HIROYUKI MIYATA,YUKINORI WADA,NAOYUKI YOKOTA
申请号:
PT08712139
公开号:
PT2123656E
申请日:
2008.02.29
申请国别(地区):
PT
年份:
2014
代理人:
摘要:
An object of the present invention is to provide prasugrel hydrochloride with a reduced content of CATP, and the like. In the formulae, R represents a protecting group for a hydroxyl group. A method for producing prasugrel hydrochloride represented by the above formula is provided, characterized by comprising, in step (i), controlling, at low values, the temperature during the addition, optionally dropwise, of a chlorinating agent and the reaction temperature after the addition, optionally dropwise, of the chlorinating agent.
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