Process for producing high-purity Prasugrel hydrochloride

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专利权人:

第一三共株式会社;宇部興産株式会社

发明人:

宮田 博之,和田 幸周,横田 尚之

申请号：

JP2009502556

公开号：

JP5363307B2

申请日:

2008.02.29

申请国别(地区):

JP

年份:

2013

代理人:

摘要：

An object of the present invention is to provide prasugrel hydrochloride with a reduced content of CATP, and the like. In the formulae, R represents a protecting group for a hydroxyl group. A method for producing prasugrel hydrochloride represented by the above formula is provided, characterized by comprising, in step (i), controlling, at low values, the temperature during the addition, optionally dropwise, of a chlorinating agent and the reaction temperature after the addition, optionally dropwise, of the chlorinating agent.

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