PURPOSE: A Caryopteris incana extract, a fraction thereof, and a compound isolated from the extract or the fraction, and a composition containing the same for protecting liver are provided to protect liver cells from hepatotoxicity caused by toxic materials and to prevent and treat liver diseases.CONSTITUTION: A pharmaceutical composition for a liver protective agent contains one or more kinds of compounds selected among compounds of chemical formulas 1-3, 5, and 8-10. The compounds protect liver cells from toxicity induced by tertiary-butyl hydroperoxide (t-BHP). A food composition for protecting liver contains one or more kinds of compounds selected among the compounds of chemical formulas 1-3, 5, and 8-10. The compound of chemical formula 1 or 2 is isolated from Caryopteris incana.COPYRIGHT KIPO 2013본 발명은 층꽃풀로부터 분리된 페놀계 화합물을 함유하는 간독성 질환 예방 및 치료용 조성물에 관한 것이다.본 발명의 층꽃풀(Caryopteris incana) 추출물, 이의 분획물 및 이로부터 분리된 화합물은 제3급-부틸히드로퍼옥시드(t-BHP, tertiary-butyl hydroperoxide)와 같은 독성 물질에 의하여 간 독성이 유발되었을 때 간세포 보호 효과가 우수하므로 간 질환의 예방 및 치료에 탁월한 효과를 기대할 수 있다.
