Bhakta, Sunil,Erickson, Hans,Junutula, Jagath R.,Kozak, Katherine,Ohri, Rachana,Pillow, Thomas
申请号：
AU2015314826
公开号：
AU2015314826A1
申请日:
2015.09.11
申请国别(地区):
AU
年份:
2017
代理人:
摘要：
Cysteine engineered antibodies comprising a free cysteine amino acid in the heavy chain or light chain are prepared by mutagenizing a nucleic acid sequence of a parent antibody and replacing one or more amino acid residues by cysteine to encode the cysteine engineered antibody； expressing the cysteine engineered antibody； and isolating the cysteine engineered antibody.
