Steven Braithwaite,Saul A. Villeda,Anton Wyss-Coray
申请号：
US15584685
公开号：
US20170232118A1
申请日:
2017.05.02
申请国别(地区):
US
年份:
2017
代理人:
摘要：
Methods and compositions are provided for screening candidate compositions for activity with respect to treatment of aging-associated conditions, e.g., cognitive impairment conditions or age-related dementia. Aspects of the methods include administering a human blood product comprising plasma, to an immunocompromised animal, e.g., a mouse or a rat, and measuring the effect of the product on an endpoint, e.g., neurogenesis, locomotor activity, anxiety, spatial memory, and hippocampus-dependent memory.
