PEPTIDE HAVING ANTICANCER ACTIVITY, AND PHARMACEUTICAL COMPOSITION AND DIETARY SUPPLEMENT COMPOSITION FOR PREVENTING AND TREATING CANCER, BOTH OF WHICH CONTAIN SAME AS ACTIVE INGREDIENT
IUCF-HYU (INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERITY)
发明人:
Chul Geun KIM,Min Young KIM,Chan Gil KIM,Ho Chul KANG,Ji Hyung CHAE,Su Jae LEE,Eun Jung BAEK,Chae Ok YUN,Jin Won LEE,Young Su LIM,Je Min CHOI,Dae Hyun HA,Hyung Sik WON,Seung Han SON
申请号：
US15563533
公开号：
US20180086788A1
申请日:
2016.03.29
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present invention relates to a peptide having an anticancer activity, and a pharmaceutical composition and a dietary supplement composition for preventing and treating cancer, both of which contain the same as an active ingredient and, more specifically, to a peptide binding to transcription factor CP2c, having an activity of preventing and treating cancer and represented by SEQ ID NO: 1, and a pharmaceutical composition and a dietary supplement composition for preventing and treating cancer, both of which contain the same as an active ingredient. <；SEQ ID NO: 1>； Asn-Tyr-Pro-Gln-Arg-Pro When cancer cells are treated with the peptide and the pharmaceutical composition containing the same, according to the present invention, the peptide can specifically bind to CP2c by passing, with very high stability, through the cell membrane and can inhibit the DNA binding ability of CP2c, thereby disturbing CP2c-mediated cancer cell-specific transcriptional activity through the inhibition of CP2c activity, and thus the present invention can be effectively used for specifically treating only cancer cells, and can be utilized for cancer prevention and as a dietary supplement additive therefor.
