The present invention relates to a pharmaceutical composition for the prevention and treatment of cancer . According to the present invention as described above , the novel benzo having apoptosis regulatory proteins of caspase (caspase) -7 growth suppression and apoptosis of cancer cells by activated functional chalcone (benzochalcone) (E-1-(2- -1- )-3-(2,3,4- ) -2- -1- , (E) -1- (2-hydroxynaphthalen-1-yl) -3- (2,3,4-trimethoxyphenyl) prop-2-en-1-one) , and pharmaceutical compositions for preventing and treating cancer comprising the same by providing , and the effect of prevention, and can be useful in the treatment of cancer .본 발명은 암 질환의 예방 및 치료용 약학조성물에 관한 것이다.상기와 같은 본 발명에 따르면, 세포사멸 조절 단백질인 카스파제(caspase)-7 활성에 의해 암세포의 성장억제 및 사멸작용을 갖는 신규 벤조칼콘(benzochalcone) 화합물(E-1-(2-히드록시나프탈렌-1-일)-3-(2,3,4-트리메톡시페닐)프로프-2-엔-1-온, (E)-1-(2-hydroxynaphthalen-1-yl)-3-(2,3,4-trimethoxyphenyl)prop-2-en-1-one) 및 이를 포함하는 암 질환의 예방 및 치료용 약학조성물을 제공함으로써, 암 질환을 예방 및 치료하는데 유용하게 사용될 수 있는 효과가 있다.