Composition comprising 3-4-Methoxybenzylaminomethylene-1,3-dihydroindol-2-one5-108 for preventing and treating the disease caused by Toxoplasmosis and Coccidium
PURPOSE: A composition containing 3-(4-methoxybenzylaminomethylene)-1,3-dihydroindole-2-one(5-108) is provided to suppress Toxoplasma gondii proliferation and to prevent and treat diseases caused by Toxoplasma gondii and coccidium. CONSTITUTION: A pharmaceutical composition for preventing and treating diseases caused by Toxoplasma gondii and coccidium contains 3-(4-methoxybenzyl amino methylene)-1,3-dihydroindole-2-one of chemical formula A and salt thereof. A veterinary composition for preventing or treating diseases caused by coccidium contains 3-(4-methoxybenzylaminomethylene)-1,3-dihydroindole-2-one(5-108) compound or pharmaceutically acceptable salt thereof as an active ingredient.본 발명은 콕시디움 억제 활성을 갖는 3-(4-메톡시벤질아미노메틸렌)-1,3-디히드로인돌-2-온(5-108)을 유효성분으로 함유하는 조성물에 관한 것으로, 상세하게는 본 발명의 3-(4-메톡시벤질아미노메틸렌)-1,3-디히드로인돌-2-온(5-108)은 콕시디움, 즉 톡소포자충의 증식에 뛰어난 억제 효과를 나타내므로 톡소포자충 및 콕시디움에 기인한 질환의 예방 및 치료에 유용하게 이용될 수 있다.
