PROBLEM TO BE SOLVED: To provide a medicine that works against toxoplasma gondii in a host cell containing bradyzoite while it has low toxicity to the host cell, and does not induce tachyzoite to bradyzoite.SOLUTION: An anti-toxoplasma agent has a compound expressed in formula (I), an isomer thereof, a pharmaceutically acceptable salt thereof or a mixture thereof as an active ingredient. (in the formula, R1 denotes H or OH, R2 denotes CH3, CH2OH, COOH or COOCH3, R3 denotes CH3 or CH2OH, and R4 denotes H or SO3 Na, a bond including a dash line denotes a single or double bond.)SELECTED DRAWING: Figure 1COPYRIGHT: (C)2018,JPO&INPIT【課題】ブラディゾイトを含む宿主細胞内のトキソプラズマ原虫に対して作用する一方で宿主細胞への毒性が低く、且つタキゾイドをブラディゾイトに誘導しない薬剤を提供する。【解決手段】式(I)で表される化合物、その異性体、薬学的に許容されるそれらの塩又はこれらの混合物を有効成分とする抗トキソプラズマ剤。(式中、R1はH又はOHを、R2はCH3、CH2OH、COOH又はCOOCH3を、R3はCH3又はCH2OHを、及びR4はH又はSO3Naをそれぞれ表し、破線を含む結合は単結合又は二重結合を表す。)【選択図】図1
