HOL, WILHELMUS G.J.,LARSON, ERIC T.,MALY, DUSTIN JAMES,VAN VOORHIS, WESLEY C.,MERRITT, ETHAN,OJO, KAYODE K.
申请号：
CA2974702
公开号：
CA2974702A1
申请日:
2016.01.26
申请国别(地区):
CA
年份:
2016
代理人:
摘要：
The present disclosure is directed to compositions and methods for inhibiting either Toxoplasma gondii (T. gondii) calcium dependent protein kinases (TgCDPKs) or Cryptosporidium parvum (C. parvum) and Cryptosporidium hominus (C. hominus) calcium dependent protein kinases (CpCDPKs) using pyrazolopyrimidine and/or imidazo[1,5-a]pyrazine inhibitors, of the Formula (I), wherein the variables X, Y, Z, R1, and R3 are defined herein.
