Douglas Gurnett Mullen,James R. Baker, JR.,Mark M. Banaszak Holl,Baohua Huang,Casey Dougherty,Jack Ball,MULLEN, Douglas, Gurnett,BAKER, Jr., James, R.,BANASZAK HOLL, Mark, M.,HUANG, Baohua,DOUGHERTY, Casey,BALL, Jack
申请号：
US14760388
公开号：
US20150352230A1
申请日:
2013.12.30
申请国别(地区):
US
年份:
2015
代理人:
摘要：
The present invention relates to novel methods of synthesis and isolation of antibodies conjugated with modular dendrimer nanoparticles. In particular, the present invention is directed to antibodies conjugated with novel modular dendrimer nanoparticles having precise numbers of imaging agents, methods of synthesizing the same, compositions comprising such antibodies conjugated with such modular dendrimer nanoparticles, as well as systems and methods utilizing the conjugates (e.g., in imaging settings) (e.g., in diagnostic and/or therapeutic settings) (e.g., for the delivery of therapeutics, imaging, and/or targeting agents).
