Provided is an immunomodulating agent for modulating abnormal immunity, particularly an excess immune response. The present inventors have made extensive studies. As a result, it is found that a mangosteen peel extract produced by extracting a mangosteen peel with a polar solvent has a function of modulating immunity, and the mangosteen peel extract is provided as an immunomodulating agent.本發明係關於為了調節免疫異常,特別是調節過剩免疫反應之免疫調節劑的提供。發明者們深入研究的結果,發現從山竹果皮以極性溶劑萃取出的山竹果皮萃取物具有調節免疫的機能,並提供此物作為免疫調節劑。