PROBLEM TO BE SOLVED: To provide a novel immunomodulator made from natural products.SOLUTION: The inventors have found out that a strain of Bacillus subtilis with a deficient spore formation ability has an immunomodulation effect and have completed this invention.SELECTED DRAWING: Figure 1COPYRIGHT: (C)2020,JPO&INPIT【課題】 本発明は、天然物由来の新規な免疫調整剤を提供する。【解決手段】 発明者らは、枯草菌の芽胞形成能欠損株に免疫調整効果があることを見出し、本発明を完成した。【選択図】図1