Wei-Zen Wei,Richard F. Jones,Joyce Reyes,Heather Gibson
申请号:
US16704679
公开号:
US20200179500A1
申请日:
2019.12.05
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Only limited success has been previously achieved from cancer vaccines targeting unmodified tumor-associated self-antigens and new compositions and methods are needed. Immunogenic compositions and methods of use thereof are provided according to the present disclosure which include a protein effective to stimulate immune activity against a tumor-associated self-antigen, or a variant thereof which is a tumor-associated self-antigen.