Disclosed herein is a pharmaceutical composition for treating depression, comprising: · a ginseng extract extracted from 3A ~10A parts by weight of a ginseng and having B% content of a ginsenoside, wherein a multiplication product of B and A is 20~40, and A is ranged between 0.2 and 40； · 0.2C ~ 0.8C part by weight of a glycyrrhizically related acid having D% purity, wherein a multiplication product of D and C is 80~98, and C is ranged between 0.8 and 98, wherein the glycyrrhizically related acid is one of a glycyrrhizic acid and a glycyrrhetic acid； and · a jujuba extract extracted from 0.05E~0.2E part by weight of a jujuba and having F% content of a jujuba cyclic adenosine monophosphate (cAMP), wherein a multiplication product of F and E is 0.5~3, E is ranged between 0.005 and 3, and the jujuba extract is one of a jujuba water extract and a jujuba ethanol extract, wherein each of B, D, and F is less than 100.
