VACCIN A BASE DE VESICULE DE MEMBRANE EXTERNE (OMV) COMPRENANT DES PROTEINES DE MEMBRANE EXTERNE DU SEROGROUPE B DE N. MENINGITIS

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专利权人:

CHIRON SPA

发明人:

PIZZA, MARIAGRAZIA,RAPPUOLI, RINO,GIULIANI, MARZIA

申请号：

CA2397508

公开号：

CA2397508C

申请日:

2001.01.17

申请国别(地区):

CA

年份:

2015

代理人:

摘要：

A composition comprising (a) Neisseria meningitidis serogroup B outer membranevesicles (OMVs), and (b) an immunogenic component selected from otherNeisseria proteins, or immunogenic fragments thereof. Component (b) preferablyincludes a protein from a different NmB strain from that from which the OMV ofcomponent (a) is derived. The OMVs are preferably obtained by deoxycholateextraction. Optionally, the composition may also comprise a protective antigenagainst other pathogens.

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