Samsung Electronics Co.; Ltd.;SAMSUNG ELECTRONICS CO LTD
发明人:
申请号:
EP14170524.4
公开号:
EP2808035B1
申请日:
2014.05.30
申请国别(地区):
EP
年份:
2018
代理人:
摘要:
A composition for target membrane protein depletion comprising a first binding domain which binds to a driver membrane protein and a second binding domain which binds to a target membrane protein, wherein the driver membrane protein and target membrane protein are associated with a cell membrane where the target membrane protein positions, and are internalized into a cell and degraded when the first binding domain of the dual binding molecule binds the driver membrane protein; as well as related methods and uses.