Cheong, Kwang Ho,Lee, Seung Hyun,Cho, Mi Young,Koh, Young Jun,Lin, Powei,Yi, Christina,Hwang, Jae Woong
申请号：
EP14170524
公开号：
EP2808035B1
申请日:
2014.05.30
申请国别(地区):
EP
年份:
2018
代理人:
摘要：
A composition for target membrane protein depletion comprising a first binding domain which binds to a driver membrane protein and a second binding domain which binds to a target membrane protein, wherein the driver membrane protein and target membrane protein are associated with a cell membrane where the target membrane protein positions, and are internalized into a cell and degraded when the first binding domain of the dual binding molecule binds the driver membrane protein as well as related methods and uses.
