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3-hydroxy-5-arylisothiazole derivative
专利权人:
Naoto Kosuga;Daido Hotta;Muneyoshi Makabe;Akihiro Okano;Munetaka Ohkouchi
发明人:
Akihiro Okano,Naoto Kosuga,Munetaka Ohkouchi,Daido Hotta,Muneyoshi Makabe
申请号:
US13392350
公开号:
US08476287B2
申请日:
2010.12.24
申请国别(地区):
US
年份:
2013
代理人:
摘要:
[Problem]To provide a GPR40 activating agent having, as an active ingredient, a novel compound having a GPR40 agonist action, a salt of the compound, a solvate of the salt or the compound, or the like, particularly, an insulin secretagogue and a prophylactic and/or therapeutic agent against diabetes, obesity, or other diseases.[Means of solving the problem]A compound of Formula (I):(where n is 0 to 2; p is 0 to 4; j is 0 to 3; k is 0 to 2; a ring A is an aryl group which is optionally substituted with L or a heterocyclic group which is optionally substituted with L; a ring B is a benzene ring, a pyridine ring, or a pyrimidine ring; X is O, S, —NR7—; and R1 to R7 are specific groups),a salt of the compound, or a solvate of the salt or the compound.
来源网站:
中国工程科技知识中心
来源网址:
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