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3-hydroxy-5-arylisoxazole derivative
专利权人:
Akihiro Okano
发明人:
Akihiro Okano,Munetaka Ohkouchi
申请号:
US13504749
公开号:
US08455500B2
申请日:
2010.10.29
申请国别(地区):
US
年份:
2013
代理人:
摘要:
[Problem]To provide a GPR40 activating agent having, as an active ingredient, a novel compound having a GPR40 agonist action, a salt of the compound, a solvate of the salt or the compound, or the like, particularly, an insulin secretagogue and a prophylactic and/or therapeutic agent against diabetes, obesity, or other diseases.[Means of Solving the Problem]A compound of Formula (I):(where p is 0 to 4 j is 0 to 3 k is 0 to 2 a ring A is a specific cyclic group a ring B is a benzene ring, a pyridine ring, or a pyrimidine ring X is —CH2—, O, —S(O)i— (i is 0 to 2), or —NR7— R1 to R6 are specific groups),a salt of the compound, or a solvate of the salt or the compound.
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