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new 3-hydroxy-5-arylisothiazole derivative
专利权人:
MOCHIDA PHARMACEUTICAL CO; LTD
发明人:
AKIHIRO OKANO,DAIDO HOTTA,MUNETAKA OHKOUCHI,MUNEYOSHI MAKABE,NAOTO KOSUGA
申请号:
BR112012015612
公开号:
BR112012015612A2
申请日:
2010.12.24
申请国别(地区):
BR
年份:
2016
代理人:
摘要:
[Problem] To provide a GPR40 activating agent having, as an active ingredient, a novel compound having a GPR40 agonist action, a salt of the compound, a solvate of the salt or the compound, or the like, particularly, an insulin secretagogue and a prophylactic and/or therapeutic agent against diabetes, obesity, or other diseases. [Means of solving the problem] A compound of Formula (I): (where n is 0 to 2; p is 0 to 4; j is 0 to 3; k is 0 to 2; a ring A is an aryl group which is optionally substituted with L or a heterocyclic group which is optionally substituted with L; a ring B is a benzene ring, a pyridine ring, or a pyrimidine ring; X is O, S, -NR 7 -; and R 1 to R 7 are specific groups), a salt of the compound, or a solvate of the salt or the compound.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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