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Heteroaryl compounds - 1,2,4 - triazole and tetrazole heteroaryl
专利权人:
Elanco Tiergesundheit AG
发明人:
TOSATTI, Paolo,WACH, Jean-Yves
申请号:
CO2018011825
公开号:
CO2018011825A2
申请日:
2018.10.31
申请国别(地区):
CO
年份:
2018
代理人:
摘要:
Compounds of formula (1) wherein: X is o or s; q u00b9 and q u00b2 are independently cr u2075 or n,Provided that at least one q u00b9 and q u00b2 is n; and a direct link or ch u2082; r u00b9 is H, alkyl, optionally substituted with a c u2081 u208b u2086 Substituent selected from: CN, conh u2082, COOH,And if no u2082 (ch u2083) u2083; haloalquilo c u2081 u208b u2086; alquenilo c u2082 u208b u2086; haloalquenilo c u2082 u208b u2086; alquinilo c u2082 u208b u2086; haloalquinilo c u2082 u208b u2086; cicloalquil c u2083 u208b u2084 cycloalkyl alkyl c u2081 u208b u2082 where c u2083 u208b u2084 is optionally substituted with 1Halo 2 Atoms; oxetan - 3 - il - ch u2082 or optionally substituted benzyl; Halo or haloalquilo c u2081 u208b u2083; R u00b2 is phenyl pyridine, pyrazine, pyrimidine, or where the phenyl pyridazine hydrochloride, pyridine, pyrimidine,Pyrazine is optionally substituted pyridazine hydrochloride or with one to three substituents, provided that the substituents are not adjacent to the Carbon Carbon joined the group of formula (2),Each independently selected from alkyl c u2081 u208b u2083, haloalquilo c u2081 u208b u2083, tiohaloalquilo c u2081 u208b u2083 c u2081 u208b u2083, alkoxy, haloalcoxi c u2081 u208b u2083, Halo, no u2082, sf u2085, CN, conh u2082,COOH and C (S) nh u2082; r u00b3 is alkyl or c u2081 u208b u2083 haloalquilo c u2081 u208b u2083; r u2074 is pyridine, pyrimidine and pyrazine or where the pyridazine hydrochloride, pyridine, pyrimidine,Pyrazine or optionally substituted pyridazine hydrochloride is a Substituent selected from: c u2081 u208b u2083 haloalquilo c u2081 u208b u2083 alkoxy alkyl, cycloalkyl, c u2081 u208b u2083, c u2083 u208b u2084, Halo or Hydroxy; r u2075 is H, alkyl c u2081 u208b u2083,Haloalquilo c u2081 u208b u2083, c u2083 u208b u2084 c u2081 u208b u2083 cycloalkyl, alkoxy, c u2081 u208b u2083c u208do u208e u208b u2092 u208d u2090 u2097 u1d9c u2092 u02e3 u2071 c u2081 u208b u2083) u2082ch alkoxy - or a Salt thereof.
来源网站:
中国工程科技知识中心
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http://www.ckcest.cn/home/

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