COMPOSÉ DE CYCLOPROPYLAMINE FLUORÉE, PROCÉDÉ DE PRÉPARATION DE CE DERNIER, COMPOSITION PHARMACEUTIQUE BASÉE SUR CE DERNIER, ET UTILISATIONS DE CE DERNIER
Shanghai Institute of Materia Medica; Chinese Academy of Sciences
发明人:
申请号:
EP17765864.8
公开号:
EP3431471A4
申请日:
2017.03.16
申请国别(地区):
EP
年份:
2019
代理人:
摘要:
Provided are a compound represented by formula I, a raceme thereof, an R-isomer thereof, an S-isomer thereof, a pharmaceutical salt thereof, and a mixture thereof, a preparation method therefor, a pharmaceutical composition comprising the compound, and uses thereof serving as an lysine specific demethylase 1 (LSD1) inhibitor. Provided are uses of the fluorinated cyclopropylamine compound represented by formula I in the treatment of cancers.