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TRANS-INDOLINE CYCLOPROPYLAMINE CHEMICAL COMPOUND, AND METHOD FOR PREPARATION, PHARMACEUTICAL COMPOSITION, AND USE THEREOF
专利权人:
Chinese Academy of Sciences;Shanghai Institute of Materia Medica
发明人:
Hong Liu,Jia Li,Wei Zhu,Yubo Zhou,Jiang Wang,Mingbo Su,Shuni Wang,Wei Xu,Chunpu Li,Weijuan Kan,Hualiang Jiang,Kaixian Chen
申请号:
US16306751
公开号:
US20190210998A1
申请日:
2017.06.02
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The present invention relates to the fields of medicinal chemistry and pharmacotherapy, and specifically relates to the chemical compound of formula (I), and its racemate, R-isomer, S-isomer, pharmaceutically acceptable salt, and mixtures thereof, as well as its method for preparation, a pharmaceutical composition containing said chemical compound, and use as a lysine-specific demethylase 1 (LSD 1) inhibitor. The cyclopropylamine chemical compound to which the present invention relates may be used in the treatment of cancer.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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