Mayo Foundation for Medical Education and Research
发明人:
MARKOVIC, Svetomir N.
申请号:
EP20170736453
公开号:
EP3399861(A1)
申请日:
2017.01.06
申请国别(地区):
欧洲专利局
年份:
2018
代理人:
摘要:
The invention described herein relates to methods for treating a patient having a plurality of HLA-negative cancer cells or cancer cells with reduced HLA expression with IFN-alpha in an amount sufficient to expand and/or activate immune cells such that the activated and/or expanded immune cells kill one or more of HLA-negative cancer cells or the cancer cells with reduced HLA expression.