CUADRADO TEJEDOR, MARIA DEL MAR,FRANCO FERNANDEZ, RAFAEL,GARCIA OSTA, ANA MARIA,OYARZABAL SANTAMARINA, JULEN,RABAL GRACIA, MARIA OBDULIA
申请号：
CA2908482
公开号：
CA2908482A1
申请日:
2014.02.27
申请国别(地区):
CA
年份:
2014
代理人:
摘要：
It relates to certain compounds having a polycyclic structure and a hydroxamic acid moiety, wherein the polycyclic structure comprises at least three ring systems, wherein one ring system is a polycyclic ring system comprising from 2 to 4 rings； at least one ring is an aromatic ring； and wherein the structure comprises at least 3 nitrogen atoms and 1 oxygen atom. It also relates to a process for their preparation, as well as to pharmaceutical compositions containing them, and to their use in medicine, in particular in the treatment and/or prevention of neurological disorders coursing with a cognition deficit or impairment, or neurodegenerative diseases. wherein B1 is a radical selected from the group consisting of formula (A"), formula (B"), formula (C"), and formula (D"):
