William Fraser SYMMANS,Bruno SINN,Christos HATZIS,Chunxiao FU,Rosanna LAU
申请号：
IL26264318
公开号：
IL262643D0
申请日:
2018.10.28
申请国别(地区):
IL
年份:
2018
代理人:
摘要：
Provided herein are methods of determining tumoral sensitivity to hormonal (endocrine) therapy based upon an index of estrogen receptor (ER)- and progesterone receptor (PR)-related genes, referred to as the sensitivity to endocrine therapy index (SETER/PR index), and may have additional consideration for the proportion of ER gene (ESRl) RNA transcripts that contain a mutation relative to the value of the SETER/PR index. Further provided are methods of treating breast cancer patients determined to be sensitive to an endocrine therapy by the SETER/PR index.
