Shanghai Institute of Pharmaceutical Industry;Zhejiang Hisun Pharmaceutical Co., Ltd.
发明人:
Fuli ZHANG,Zhezhou YANG,Rusheng BAO,Weiwei XU,Hua BAI
申请号：
US16014678
公开号：
US20180297998A1
申请日:
2018.06.21
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Intermediate compounds for the preparation of Praziquantel are provided. In particular, the intermediate compounds provided include a compound of formula (IV) and a compound of formula (V). Also provided are processes for preparing the intermediate compounds. Additionally, the raw materials are inexpensive and easy to obtain, the key intermediates are easy to prepare, and the total reaction yield and purity of the obtained target compound Praziquantel is high, so that industrialized mass production of Praziquantel using the intermediate compounds is easy to achieve.
